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Duke Leads NCAA Tournament Odds Despite Dual Starter Injuries

By Matthias Binder March 17, 2026
Oddsmakers install Duke as favorite to win NCAA Tournament despite injuries
Oddsmakers install Duke as favorite to win NCAA Tournament despite injuries (Featured Image)
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Oddsmakers install Duke as favorite to win NCAA Tournament despite injuries

Contents
Duke’s Grit Shines Through AdversityNavigating the Injury LandscapeBracket Breakdown and Early EdgesChasing the Blue Devils: Top RivalsCinderella Watch and Market Buzz

Duke’s Grit Shines Through Adversity (Image Credits: Pixabay)

Las Vegas – Duke’s men’s basketball team heads into March Madness missing two starters to injuries yet holds the top spot on betting boards. Caesars Sportsbook installed the Blue Devils as favorites at +295 to win the national championship, reflecting confidence in their depth and momentum.[1] The squad earned the No. 1 overall seed in the East Region after capturing the ACC Tournament title on an 11-game winning streak.

Duke’s Grit Shines Through Adversity

Few expected Duke to navigate the ACC Tournament without key pieces, yet the Blue Devils prevailed. They defeated Florida State 80-79 in the quarterfinals, Clemson 73-61 in the semifinals, and Virginia 74-70 in the championship game.[2] Freshman Cayden Boozer emerged as a steady hand, posting career-high 16 points in both the semifinal and final while logging all 40 minutes in the title clash.

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The team adjusted swiftly to the absences, leaning on Boozer’s poise at point guard and collective defensive effort. This run affirmed Duke’s status as the nation’s top-ranked team by KenPom, boasting elite offensive and defensive efficiency ratings.[3] Their opener against No. 16 Siena on Thursday carries a 28-point spread, underscoring the market’s faith.

Navigating the Injury Landscape

Starting guard Caleb Foster underwent surgery for a broken right foot suffered against North Carolina on March 7. Coach Jon Scheyer noted Sunday that Foster’s return “will be a little while still,” making his availability unlikely before the Final Four at earliest.[1][4] Starting center Patrick Ngongba deals with foot soreness that sidelined him for the regular-season finale and the entire ACC event.

Ngongba progressed through therapy during the conference tournament and remains day-to-day. Scheyer described his recovery as steady, tied to medical benchmarks. Both players supported from the bench in matching hoodies and boots, signaling team unity amid the challenges.[4]

Bracket Breakdown and Early Edges

Duke’s East Region path starts favorably, with Siena representing a typical top seed mismatch. The tournament culminates April 6 at Lucas Oil Stadium in Indianapolis. Oddsmakers anticipate a “chalky” bracket, mirroring last year’s results where top programs dominated.[1]

Line movement already hinted at volatility elsewhere. Alabama’s spread over Hofstra dropped from 14.5 to 11.5 after an arrest involving guard Aden Holloway. Bettors sharpened focus on games like Iowa State minus 24 over Tennessee State and UConn minus 21 versus Furman.

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Chasing the Blue Devils: Top Rivals

Michigan follows at +360, hampered by backup point guard L.J. Cason’s torn ACL. The Wolverines, No. 1 in the Midwest, fell to Purdue in the Big Ten final and face the UMBC-Howard play-in winner.[1] Arizona sits at 4-1 (+400 across books), riding a nine-game streak after sweeping the Big 12; they open as 30.5-point picks over Long Island.

Team Odds (Caesars/DraftKings) Seed/Region
Duke +295 / +330 No. 1 East
Michigan +360 / +350 No. 1 Midwest
Arizona 4-1 / +400 No. 1 West
Florida +650 / +700 No. 1 South

Florida, the defending champion with a 26-7 mark, earned the South’s top seed despite a SEC semifinal upset.[5] Caesars trader Patrick Berbert praised their experience: “With a roster full of experienced players, they’ll be a tough out.”[1]

Cinderella Watch and Market Buzz

Potential mid-majors could spice the bracket. South Florida, a No. 11 seed with a 25-8 record under coach Bryan Hodgson, drew notice for its pace-and-space style; they face No. 6 Louisville as 5.5-point underdogs.[1]

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  • Saint Louis (28-5, No. 9 seed): 2.5-point underdogs to Georgia.
  • Miami (Ohio) (No. 11, First Four): +240 moneyline versus SMU.
  • Berbert highlighted these for betting interest, alongside NIL-driven talent gaps favoring elites.

High-action openers include SMU-Miami (Ohio), Utah State-Villanova, and High Point-Wisconsin. Berbert forecasted record wagering, fueled by the most-watched regular season ever.

Key Takeaways

  • Duke’s +295 odds at Caesars signal strong belief despite Foster and Ngongba out.
  • Four No. 1 seeds dominate the top of the market, pointing to a top-heavy field.
  • Watch for young talents like Cayden Boozer to sustain Duke’s streak.

Duke’s ability to thrive short-handed positions them for a deep run, but the field’s depth tests every contender. As brackets fill and games tip off, the Blue Devils’ resilience could define this March Madness. What do you think about Duke’s title chances? Tell us in the comments.

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