Movie sets are built on teamwork, at least on paper. Dozens of people have to cooperate for months, and the actors at the center are expected to sell chemistry no matter how they feel about each other.
Sometimes that doesn’t work out. Over the decades, a handful of famous pairings have reportedly gone to real lengths to avoid each other on set. Some of these stories are confirmed by the actors themselves, and others rest on crew gossip or on claims the stars have disputed.
Dwayne Johnson and Vin Diesel, The Fate of the Furious

In a since-deleted 2016 Instagram post, Dwayne Johnson called some of his male costars on The Fate of the Furious names, which sparked speculation about a feud with Vin Diesel. In 2018, Johnson confirmed that the two didn’t film any scenes together.
Johnson has described the split as a difference in how each man approaches filmmaking and collaboration. When the film came out, some viewers suggested the scenes were edited to hide that the two weren’t on set together. Johnson later declared a truce and appeared in Fast X.
Julia Roberts and Nick Nolte, I Love Trouble

The 1994 comedy I Love Trouble was meant to echo the screwball romances of the 1940s. Roberts and Nolte played rivals who team up and then fall in love. Off camera, the dynamic was far less charming.
Because of their dislike for each other, stand ins were reportedly used as often as possible, and various scenes were filmed separately. The feud was still alive in 2009, when Roberts gave a profanity filled impression of a former costar on The Late Show, and it turned out to be Nolte.
Julianna Margulies and Archie Panjabi, The Good Wife

Rumors of tension between these two Good Wife stars ran for years. Reports noted they didn’t share a single scene during the show’s final three seasons, until the Season 6 finale. That finale reunion is where the story really took off.
In Panjabi’s last episode, the two characters reunited by split screen. Margulies publicly denied any bad blood. She said the scene was shot that way because of scheduling conflicts. Panjabi disagreed, saying she was ready to film the scene in New York at the time.
Lena Headey and Jerome Flynn, Game of Thrones

Fans noticed that Cersei Lannister and Bronn almost never shared the screen. A crew member reportedly claimed the two stars wouldn’t even be in the same room. A bad breakup between the actors was blamed for the situation.
The story is murkier than it sounds. Flynn acknowledged in 2019 that they had once been a couple. He pushed back on the idea that things stayed hostile, saying they had appeared together in at least one scene. The popular claim that their contracts barred shared scenes remains unverified.
Orson Welles and Peter Sellers, Casino Royale

The 1967 spoof Casino Royale was famously chaotic, and its two stars were part of that. Welles and Sellers reportedly refused to film together and avoided being on set at the same time. Sellers allegedly left the set altogether to avoid Welles.
This is one of the older accounts on the list, and the details come largely from decades of retelling. It’s worth treating the specifics with some caution. Still, the idea that these two rarely overlapped is a regular part of the film’s backstage lore.
Helen Hunt and Bill Paxton, The Twister Ride

Hunt and Paxton starred together in the 1996 disaster film Twister. Years later, they were asked to record safety messages for a theme park attraction based on the movie. Guests saw their filmed warnings before the ride, but the two reportedly wouldn’t film the brief scripted interaction together and were shot separately.
Insiders claimed they didn’t want to share the screen. Neither star has been widely quoted explaining why, so the motive remains a matter of reports rather than confirmed fact. Because this involved a ride video rather than the movie itself, it’s a slightly different case from the others here.
Wesley Snipes and Ryan Reynolds, Blade: Trinity

Blade: Trinity became nearly as famous for its behind the scenes stories as for the film. Patton Oswalt said Snipes refused to leave his trailer for much of the shoot and only came to set for his close ups. Reynolds’ improvisational style reportedly clashed with Snipes’ approach.
The story has an unexpected ending. Snipes returned as Blade in Deadpool & Wolverine, appearing alongside Reynolds nearly two decades after Blade: Trinity. Snipes later said the reunion helped resolve their old rivalry.